| Character Information
|First seen:||Manga: Chapter 1|
Anime: Episode 1
|Last seen:||Manga: Chapter 1|
Anime: Episode 1
|Voice actor (Japanese):||Maria Yamamoto|
|Voice actor (English):||Tiffany Grant|
|“||Someday, I'll be the best secretary in Japan. One who can be at our chief's side and help him out.||”|
–Kisaragi, wanting to be of use to Kurama
Kisaragi was Kurama's secretary in the island facility that held and experimented on Diclonius, including Lucy. A graduate of the famed and prestigious Todai (University Of Tokyo), she was apparently a good secretary, but lacked confidence and was very clumsy. She was also extremely devoted to her boss.
Kisaragi was hired by Kurama despite the doubts of many other people, and at times, despite doubts held by other staff about Kurama. It's known that Kurama kept a picture of her next to ones of his late wife Hiromi and Nana, whom he considered like his own daughter. The affection between the two seemed familial and genuine. It was Kisaragi who told her boss that Hiromi, pregnant with their daughter Mariko had been taken to the hospital with complications.
During Lucy's escape at the start of the series, she literally stumbled into a firefight between Lucy and the facility's guards, and was seized by Lucy as a hostage. In the manga, Kurama explains to Kisaragi that he cannot allow Lucy to escape, and must fire through her. Kisaragi accepts this with grace, but Lucy quickly decapitates her and uses her body as a shield against the guards' gunfire, taunting Kurama that her death was now meaningless. Kurama, enraged by Lucy's act, vows to take revenge upon her. In the anime, Kiasragi's death is not as dramatic. Lucy merely decapitates her the instant she realizes Kurama, who she hates, is fond of her.
Kisaragi is later seen in flashbacks set prior to the start of the series. Kisaragi is among the most notable casualties of the memorably violent first ten minutes of the anime's first episode, and like many others, her death is shown in greater detail in the anime. Her death is one of many things that drive the bitter enmity between Lucy and Kurama.
- The design for Kisaragi's look and character may have been inspired by Love Hina's Mutsumi Otohime, who was also known for being a sweet airhead as well as more than a bit clumsy. Both characters are also depicted with long hair bangs, and Mutsumi was at least a student at Tokyo University, and was doing graduate work as the series ended.
- Maria Yamamoto is Kisaragi's voice actress in the anime, and also voiced Kanae and Saito, all of whom had memorably gruesome deaths.